MosaicDM LLC Dimensional Intelligence Framework · SoundBiology · Zenodo 18928388 · Dr. Dan Fort April 2, 2026
DI Analysis Report

Synthetic FHIR
Multimodal Ophthalmic
Dataset

Dimensional Intelligence decomposition of a linked synthetic care graph: patient, hospital, and practitioner FHIR bundles combined with fundus and OCT imaging across three format layers — FHIR Media, JPEG, and DICOM.

5 evidence layers confirmed FHIR R4 · LOINC · SNOMED · US Core Synthetic only — not clinical truth
Dataset Manifest
Patient bundle entries2,143
Observation resources905
Procedure resources238
Claim + EOB pairs155 × 2
DiagnosticReport153
Encounter105
ImagingStudy16
Media (embedded img)12
DICOM filesMultiple
ClassificationConfidential
01

Dataset Summary

Bundle entries
2,143
Patient longitudinal chart · life-course from birth to 2024
Imaging assets
16+ studies
12 Media resources · standalone DICOM · JPEG renders
Billing artifacts
310
155 Claim + 155 EOB · end-to-end reimbursement testable
DI evidence layers
5
Identity · chronology · imaging · provider · billing
02

Multimodal Evidence Dimensions

D1 · FUNDUS
2D Surface
R+2
Vessel structure, optic disc, macula. 1024×1024 JPEG. Minor acquisition artifact (central shadow). Sufficient for screening — not surgical fidelity.
D2 · OCT
Cross-Sectional
R+3
Retinal layer integrity, foveal contour, depth information. 512×512 JPEG. Higher diagnostic signal than fundus — critical differentiator.
D3 · FHIR
Structured Data
High
Diagnoses, coded observations, DiagnosticReport, billing. LOINC + SNOMED + US Core compliant. Standards-oriented synthetic data.
D4 · PROVIDER
Attribution
Weak*
Org linkage, referral chains, NPI-style IDs. *NUCC specialty codes unreliable — many coded as General Practice despite ophthalmic org names. Synthetic artifact.
DI non-interchangeability rule: These dimensions are never conflated. Fundus ≠ OCT ≠ structured report ≠ coded observation ≠ billing artifact. Cross-modal output must declare one of three states: Agreement · Disagreement · Unresolved. Collapse is the failure mode this system is built to prevent.
03

Care Graph — Concept Map

all nodes connected via deterministic FHIR references — no fuzzy inference permitted Patient Root entity · Synthea · born 1965-06-12 Encounter Temporal anchor · 105 total · annual ophth cadence ImagingStudy DICOM bridge · 16 studies Procedure Eye exam · OCT · 238 total Condition DM2 · NPDR · Neuropathy Claim + EOB 155 pairs · billing layer DiagnosticReport OCT + retinopathy · 153 DICOM Canonical source Media FHIR payload Observation Left/right LOINC coded ImagingStudy UID linkage · DICOM Practitioner · Role · Organization · Location Attribution layer · NPI-style IDs · NUCC taxonomy imaging layer clinical findings layer
04

Temporal Decomposition

Chronic disease progression timeline — life-course longitudinal synthetic data
1987
Prediabetes
Initial metabolic anomaly — begins disease trajectory
2020
Type 2 Diabetes Mellitus
Confirmed · annual ophthalmic surveillance begins
2021
Neuropathy due to Type 2 DM
Systemic complication — confirms progression pattern
2023
Nonproliferative Diabetic Retinopathy (NPDR)
Due to Type 2 DM · ophthalmic complications established
2024-05-17
Complete Multimodal Event Cluster
Encounter → Procedure (exam + OCT) → ImagingStudy → DiagnosticReport → Observation (left/right OCT + retinopathy severity) → Claim + EOB. Full five-layer record in a single date.
05

Cross-Modal Consistency — 2024-05-17

Evidence signal by modality
OCT observations (structured LOINC coded) No abnormal findings
Fundus imaging (visual assessment) No strong pathology detected
Structured FHIR diagnosis (SNOMED coded) Mild NPDR confirmed
DI output — correct
"Mild retinopathy present per structured clinical data; imaging does not show strong advanced features — consistent with early-stage NPDR below JPEG resolution threshold."
✕ "No disease" — image-only collapse error
✕ "Disease confirmed visually" — overclaim from image alone
Four-dimensional confidence scoring
SC
Structural confidence
DICOM UID → ImagingStudy; Practitioner → Encounter performer; Media → DiagnosticReport
CS
Clinical signal confidence
Fundus image quality score; OCT availability; report/observation agreement
TC
Temporal confidence
Procedure before billing; imaging before interpretation; diabetes onset before retinopathy
AC
Attribution confidence
Capturing / ordering / interpreting provider per imaging study; facility of service
Composite score produced only after all four sub-scores are resolved
06

Deterministic Ingestion Pipeline

A · PARSE Canonical FHIR · DICOM · JPEG B · RESOLVE Entity Ref · UID · Timestamp C · PROVENANCE Lock Source · Ver · Confidence D · SEPARATE Modalities Fundus/OCT/Struct/Bill E · CONSISTENCY Cross-Modal Agree/Disagree/Unresolved F · OUTPUT JSON Object Client-safe · Bounded deterministic at every stage · no fuzzy merge without explicit confidence downgrade · provenance stamped on every node
07

Competitive Differentiation

Approach What they output DI / MosaicDM
Image AI only "No disease" — JPEG classifier result, FHIR diagnosis ignored Cross-modal reconciliation: image + coded report + structured finding
FHIR ETL only "Disease present" — structured data alone, no imaging context Full provenance graph with modality-separated evidence at every node
Clinical dashboard Shows both layers with no reconciliation logic — user resolves disagreement Deterministic consistency engine: Agreement / Disagreement / Unresolved — explicitly labeled
Note summarization AI Summarizes text — loses imaging and billing context entirely Bounded conclusions scoped to confirmed signal strength across all four dimensions
Core differentiator: Deterministic graph assembly + modality-separated evidence handling + traceable provider attribution + bounded conclusions. Every competitor collapses dimensions. DI is the only framework built to prevent that collapse. This is not an ophthalmology AI — it is a domain-agnostic deterministic multimodal clinical reasoning engine whose first domain is ophthalmology.
08

DI Guardrails — System Level

IC
Information Conservation
Do not infer disease severity beyond available signal. A single JPEG cannot support strong disease claims. Signal scope determines conclusion scope — always. The image is one evidence dimension, not the arbiter.
DC
Dimensional Coherence
Maintain hard separation between modalities: 2D fundus image, cross-sectional OCT, structured coded findings, clinical note text, billing artifacts. These are different dimensions of evidence — not interchangeable representations of the same truth.
EB
Evidence Boundary
Cap conclusions at the strongest confirmed layer. When image suggests mild findings, OCT report says no abnormal findings, and structured diagnosis says mild NPDR — the output must preserve the disagreement rather than collapsing to a single label. Disagreement is data.
09

Client-Facing Output Schema

"patient_id": "...",
"episode_id": "...",

"modalities_present": ["fundus_jpeg", "dicom", "fhir_media", "observations", "diagnostic_report", "claim"],

"provider_context": {
  "performing_org": "HARBORVIEW MEDICAL CENTER",
  "linked_practitioners": [...],
  "attribution_confidence": 0.84
},

"imaging_summary": {
  "fundus_quality": "usable",
  "dicom_present": true,
  "oct_present": true,
  "laterality_resolved": ["left", "right"]
},

"clinical_summary": {
  "structured_findings": [...],
  "report_findings": [...],
  "image_only_findings": [...]
},

"consistency_check": {
  "agreement": [...],
  "disagreement": ["mild NPDR in structured data; not confirmed visually"],
  "needs_review": [...]
},

"trace": {
  "source_files": [...],
  "resource_ids": [...],
  "linkage_paths": [...]
}
10

DI Utility Bounds

High-value applications
Validating multimodal FHIR ingestion pipelines
Building patient-centric graphs across encounters, studies, images, and billing
Testing image extraction and indexing from FHIR Media
OCT/fundus linkage to structured FHIR findings
Simulating diabetic retinopathy longitudinal surveillance workflows
Validating joins between patient bundles and provider/location registries
Building demo dashboards and synthetic sandboxes — no PHI risk
Proving the DI cross-modal consistency engine approach
Do not use for
Real-world epidemiologic truth or disease prevalence inference
Clinical performance claims without external validation
Specialty routing based on NUCC codes — synthetic artifact, unreliable
Ground-truth imaging assessment — synthetic generation inconsistencies present
Causal medical conclusions beyond what DI analysis confirms
Production diagnostic performance benchmarking
Confirmed synthetic data — not ontologically equivalent to real care data